A mild and efficient method for trimethylsilylation of alcohols with hexamethyldisilazane (HMDS) catalyzed by TETRABUTYLAMMONIUM BROMIDE is reported. The method is highly chemoselective for the o-protection of primary and secondary alcohols in the presence of amines, thiols and tertiary alcohols.

BACKGROUND AND OBJECTIVE: Most of the anticholinergic agents abuse are among the medications used for the treatment of neuroleptics induced parkinsonism. These drugs are abused orally or parenterally in psychiatric patients dominantly in psychotic patients. We reported a case of anticholinergic drug dependence in a patient who received it for reduction of withdrawal symptoms but abused it by smoking later.CASE: A 25 year old opioid dependent man previously treated with methadone referred to psychiatry clinic for detoxification of opioids. But he abused prescribed Hyoscine-NBB tablets by smoking willfully in order to reduce nausea and abdominal pain. He continued to abuse because of its euphorogenic effects and withdrawal symptoms such as restlessness, anxiety, insomnia and loss of appetite appeared when he discontinued. During 16 days of admission maintenance methadone therapy began to treat the opioid dependence and hyoscine was tapered concurrently. Despite significant improvement he did not follow the treatment when discharged.CONCLUSION: Anticholinergic medications may be potentially abused when prescribing for relief of withdrawal symptoms in substance detoxification.

A spectrophotometric study concerning the interactoin between iodine and bromine with TETRABUTYLAMMONIUM iodide (TBAI), tetrabutyl- ammonium BROMIDE (TBABr) and cryptand 222 (C222) has been performed in dichloromethane solution at 25°C. The results are indicative of the formation of TBA+X3 - and C222X+X3 - through equilibrium and formation of C222X+X- through nonequilibrium reactions. The stability constants of the equilibrium reactions were evaluated from the computer fitting of the absorbance-mole ratio data. It was found that iodine complexes were more stable than bromine ones. Comparision of the spectra of I2-TBAI with the I2-C222 mixtures indicates that the isosbestic points of the two systems are not identical. A similar behavior is observed for the corresponding bromine spectra. Comparision of the spectra of iodine complexes with those of bromine also indicates that in the spectra of iodine complexes 1) the wavelength of the isosbestic point is less than λmax of the free iodine and 2) addition of C222 or TBAI decreases the absorption intensity at λmax of iodine. However, in each case the reverse is observed for the spectra of bromine complexes. The possible reasons for the observed differences in various spectra are explained.  

In this research, a highly effective approach is introduced for the improvement of carbon-carbon coupling through Ullmann reaction to synthesize a variety of biaryl compounds with a level of efficiency ranging from good to excellent. To achieve this objective, the compound 4′-(4-methoxyphenyl)-2,2′:6′,2″-terpyridine (Mtpy) was employed as a tridentate ligand with electron-rich properties and CuI served as the catalytically active sites. In the investigated reaction, a combination of N,N-Dimethylethylenediamine (DMED) and TETRABUTYLAMMONIUM BROMIDE (TBAB) was utilized as a novel Deep Eutectic Solvent (DES), fulfilling triple roles: functioning as a base, facilitating the reaction process as an additive, and plays its main role as a solvent for the carbon-carbon coupling reaction. The results acquired are compared with existing literature reports, demonstrating the efficacy of the approach. Furthermore, the triple functionality of the deep eutectic solvent, coupled with its capability to be recovered three times during the reaction, highlights its robustness under reaction conditions and presents promising opportunities in the field of green chemistry.

Spinel magnesium Cobaltite (MgCo2O4) nanoparticles with a crystalline size in the range of ∼ 16 nm were prepared by a simple co-precipitation technique with NaOH as a precipitant. The formation of spinel MgCo2O4 phase was confirmed by X-ray diffraction (XRD) pattern. Scanning electron microscope (SEM) images showed that aggregated nanoplates. The electrochemical performance of modified MgCo2O4 electrodes was investigated with 2M of TETRABUTYLAMMONIUM perchlorate (TBA) electrolyte. The cyclic voltammetry (CV) results revealed that the MgCo2O4 electrode reached the highest specific capacitance of 390 ° F/g at a scan rate of 5mV/s. The excellent electrochemical performance was absorbed due to the electrochemical faradaic redox reactions related to the intercalation/de-intercalation of the TETRABUTYLAMMONIUM cation (TBA+) and MgCo2O4 lattice, and brings an additional pseudocapacitive contribution. The present work proves that the prepared magnesium cobaltite can serve as advanced electrode material for next generation organic electrolyte supercapacitors.